Low Dose Oral Minoxidil For Hair Loss Compounding Options
Pavilion Compounding Pharmacy is once again meeting the needs of our patients by offering minoxidil in lower doses than is used for treating high blood pressure.
The use of LDOM for hair loss was initially investigated by Rodney Sinclair, MD, professor of dermatology at the University of Melbourne. He conducted a pilot study and suggested the use of oral minoxidil (0.25 mg) in conjunction with spironolactone (25 mg) as a safe and effective treatment for female pattern hair loss. Dosing for women ranged from 0.25mg to 2.5mg and men are higher, around 2.5mg to 5mg.
It is important to treat with lower doses to avoid the side effects from minoxidil which includes Hypertrichosis, swelling of the feet and increased heartbeat. Using the lower doses orally, in contrast to the topical minoxidil formulations is considered off label. However, the success rate according to the study shows greater than 65% according to Dr. Michael Gold, MD, medical director of Gold Skin Care Center in Nashville, Tennessee.
While the mechanism of action is complex, suffice to say it works by increasing the uptake of the amino acid cysteine into the hair bulb outer root sheath, thus strengthening and increasing fiber integrity.
With lower dose formulations and compounding it is important to have a uniform, consistent mixture to provide reproducible results. At Pavilion Compounding Pharmacy, LLC, we use the most advanced blending equipment in the industry to formulate minoxidil and the many other medications we compound.
Located in Atlanta, GA Pavilion Compounding Pharmacy, LLC provides both sterile and non-sterile compounding and we are PCAB accredited.
Low dose oral minoxidil requires a prescription and we accept orders via fax, telephone, and via electronic prescribing. We can only ship to states we are licensed, which includes, Georgia, Florida, Tennessee, New Jersey, New York, and North and South Carolina.
Pavilion Compounding Pharmacy, LLC
3200 Downwood Circle, NW Suite 210
Atlanta, Georgia 30327
Villani A, Fabbrocini G, Ocampo-Candiani J, Ruggiero A, Ocampo-Garza SS. Review of oral minoxidil as treatment of hair disorders: in search of the perfect dose. J Eur Acad Dermatol Venereol. 2021;35(7):1485-1492. doi:10.1111/jdv.17216
Beach RA, McDonald KA, Muylaert Barrett B. Low-dose oral minoxidil for treating alopecia: a 3-year North American retrospective case series. J Am Acad Dermatol. 2021;84(3):761-763. doi:10.1016/j.jaad.2020.10.032